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Navigating the Maze of Pathology Scanners

At its core, digital pathology involves converting glass slides into digital images that can be viewed and analyzed using computer software. This process offers numerous advantages over traditional microscopy, including the ability to share and collaborate on images remotely, analyze large datasets, and improve diagnostic accuracy. However, one of the key challenges in digital pathology is choosing the right scanner to capture high-quality digital images of tissue specimens. With so many options available on the market, finding the right scanner for your lab can be a daunting task. This requires careful consideration of factors such as purpose, throughput, resolution, compatibility, cost, and support and maintenance. PathPixel is here to help you choose a scanner that meets your specific requirements and supports your digital pathology efforts.

Company
Model
Slide capacity
Image mode
Frozen ROSE
Image Format
Barcode
Scan Mode
Scan Speed at 40X
Dimension
Weight
Certifications
3DHistech
PANNORAMIC 480 DX
480
Brightfield
No
DICOM, MRXS
1D,2D
1200 W mm x 902 D mm x 1004 Hmm
240kg
3DHistech
PANNORAMIC SCAN II Legacy
150
Fluorescence, Brightfield
No
DICOM, Tiled TIFF
Barcode scanning
3DHistech
PANNORAMIC Flash DESK DX
1
Brightfield
Yes
DICOM, MRXS
30 sec
38W
12kg
Not FDA approved
3DHistech
PANNORAMIC DESK II DW Legacy
1000
Fluorescence, Brightfield
Yes
DICOM, Tiled TIFF
Z-Stack
27 cm x 50 cm x 25.5 cm
11kg
3DHistech
PANNORAMIC Midi II Legacy
12
Fluorescence, Brightfield
Yes
DICOM, Tiled TIFF
Barcode scanning
3DHistech
PANNORAMIC 250 Flash III DX
300
Fluorescence, Brightfield
No
MRXS,DICOM, Tiled TIFF
Barcode
3DHistech
PANNORAMIC 1000 FLASH DX
1000
Brightfield
No
DICOM, MRXS
1D,2D
Z-Stack
32sec
Glissando
Glissando Desktop Scanner
2
Brightfield
Yes
SWS, SVS, SZI, TIFF/BigTIFF with user-configurable compression
Image-based 1D and 2D (Datamatrix, QR code)
Z-Stack
0.275 µm
320W x 297H x 447D mm
Glissando
Glissando POL
2
Fluorescence, Brightfield
Yes
SWS, SVS, SZI, TIFF/BigTIFF with user-configurable compression
Image-based 1D and 2D (Datamatrix, QR code)
Z-Stack
0.275 µm
320W x 297H x 447 D mm
CE-IVD, RUO
Glissando
Glissando 20SL
20
Brightfield
Yes
SWS, SVS, SZI, TIFF/BigTIFF with user-configurable compression
Image-based 1D and 2D (Datamatrix, QR code)
Z-Stack
32W x 32 H x 55D mm
CE-IVD, RUO
Grundium
GRUNDIUM OCUS®20
20
Brightfield
Yes
SVS, TIFF, JPG
NA
1min
W 18 x D18 x H19 cm / 7x7x7.5 inches
3,5 kg /7,7Lbs
Grundium
GRUNDIUM OCUS®40
40
Brightfield
Yes
TIFF, SVS, JPG
NA
13mins
W 18 x D18 x H19cm / 7x7x7.5 inches
3,5 kg /7,7Lbs
CE-IVD, RUO
Hamamatsu
Nano Zoomer S60
60
Fluorescence, Brightfield
No
JPEG compression
Z-Stack
150 Seconds
68 W x 700H mm
79kg
Hamamatsu
Nano Zoomer S210
210
Brightfield
No
JPEG compression
Z-Stack
150Seconds
780x583x636.5 mm
69kg
Hamamatsu
Nano Zoomer S360
360
Brightfield
No
JPEG compression
Z-Stack
30Seconds
750x628x690 mm
78kg
Hamamatsu
Nano Zoomer S20
20
Brightfield
Yes
JPEG compression
1D Code :39, code128, EAN 8 & UPC-E. 2D Code: DataMatrix (ECC200) QR Code (QR cod model 2)
Z-Stack
0.23 µm
615 L x 450H x 425W mm
52 kg
Hamamatsu
Nano Zoomer -SQ
1
Brightfield
Yes
JPEG compression
Z-Stack
275 Seconds
360WX380HX450D mm
20kg
Huron
Tissue Scope iQ
400
Brightfield
No
Non-proprietary 24-bit RGB Pyramidal BigTIFF, DICOM compatible Uncompressed, or JPEG 2000 Compression Export to JPEG, Flat TIFF and LZW Compressed TIFF
Image based barcode reading
Z-Stack
0.2 µm
60W x54L x 43H cm
34 kg 97Lbs
Huron
TissueScope™ LE120
120
Brightfield
No
Non-proprietary 24-bit RGB Pyramidal BigTIFF Uncompressed, or JPEG 2000 Compression Export to JPEG, Flat TIFF and LZW Compressed TIFF
Image based barcode reading
Z-Stack
<1min/slide
89x60.5x74.5cm
68kg 150Lbs
CSA/UL/CE
Huron
Tissue Scope LE
120
Brightfield
No
Non-proprietary 24-bit RGB Pyramidal BigTIFF Uncompressed, or JPEG 2000 Compression Export to JPEG, Flat TIFF and LZW Compressed TIFF
Image based barcode reading
Z-Stack
0.2 µm
61.0W x56LX40cm
39kg /85Lbs
CSA/UL/CE
Huron
TissueSnap™ Preview Station
120
Brightfield
Non-proprietary 24-bit RGB Pyramidal BigTIFF Uncompressed, or JPEG 2000 Compression Export to JPEG, Flat TIFF and LZW Compressed TIFF
34.0Wx22.3Lx 37.5H cm
6.8kg /15Lbs
CSA/UL
KFBIO
KF-FL-400
400
Fluorescence, Brightfield
No
KFB / TIFF / SVS
Barcode / QR
Line Scanning
≤0.25µm
KFBIO
KF-PRO-120
120
Fluorescence, Brightfield
No
KFB / TIFF / SVS
Barcode / QR
Z-Stack
≤0.25µm
KFBIO
KF-PRO-400
400
Brightfield
No
KFB / TIFF / SVS
Barcode / QR
Z-Stack
≤0.25µm
KFBIO
KF-FL-120
120
Fluorescence, Brightfield
No
KFB / TIFF / SVS
Barcode / QR
Line Scanning
≤0.25µm
KFBIO
KF-FL-005
5
Fluorescence, Brightfield
Yes
KFB / TIFF / SVS
Barcode / QR
Line Scanning
≤0.25µm
KFBIO
KF-PRO-040
40
Brightfield
Yes
KFB / TIFF / SVS
Barcode / QR
Z-Stack
≤0.25µm
KFBIO
KF-PRO-005
5
Fluorescence, Brightfield
Yes
KFB / TIFF / SVS
Barcode / QR
Line Scanning
0.25µm
KFBIO
KF-PRO-020
20
Brightfield
Yes
KFB / TIFF / SVS
Barcode / QR
Z-Stack
≤0.25µm
KFBIO
KF-PRO-002
2
Brightfield
Yes
KFB / TIFF / SVS
Barcode / QR
Line Scanning
≤0.25µm
Leica
Aperio VERSA
8
Brightfield
Yes
SVS
Barcode
Leica
Aperio AT2
400
Brightfield
No
SVS
1D and 2D Symbology
155 seconds
23.5 H x 16 W x 25.5 D inches 59.7 cm H x 40.6 cm W x 64.7 cm D
63.5 kg 140Lbs
Leica
Aperio LV1
4
Brightfield
Yes
SVS
Barcode scanning
Leica
Aperio AT Turbo
400
Brightfield
No
SVS
1D and 2D Symbology
310 seconds
23.5 H x 16 W x 25.5 D inches 59.7 H x 40.6 W x 64.7 D cm
58.5 kg129Lbs
Leica
Aperio GT 450
450
Brightfield
No
SVS / TIFF
1D and 2D Symbology
32 seconds
52.83 cm x 58.43 cm x 49.53 cm 20.8 in x 23 in x 19.5 in
63.5 kg140Lbs
Leica
Aperio CS2
5
Brightfield
Yes
SVS
Z-Stack
12.5 W x 19 H x 20.5 i D inches318 x 465 x 502 mm
 25 kg  55Lbs
Leica
Aperio XT
120
Brightfield
No
SVS
1D and 2D Symbology
600 seconds
23.5 Hx 16 Wx 25.5 D inches 597 mm Hx 406 mm W x 648 mm D
47.6 kg 105Lbs
Morphle
Hemolens - true 100x oil scanner
6
Brightfield
No
Z-Stack
3.5min
19Wx 17.5Dx 20H inch
50 Kg110 lb
Morphle
MorphoLens 6
6
Brightfield
Yes
Linear type: CODE 39, CODE 128 Matrix: QR code, PDF417
Z-Stack
16W x 18D x 14H inch
26 Kg 57 lb
Morphle
MorphoLens 240
240
Brightfield
Yes
Linear type: CODE 39, CODE 128 Matrix: QR code, PDF417
Z-Stack
31 Wx 28 Dx 30H inch
100 Kg 220 lb
Morphle
MorphoLens 1
1
Brightfield
No
Linear type: CODE 39, CODE 128 Matrix: QR code, PDF417
Z-Stack
240 sec
16W x 18D x 14H inch
26 kg 57 lb
Motic
MoticEasyScan Pro 6
6
Brightfield
Yes
Jpg2000,SVS
Image-based 1D and 2D (Datamatrix, QR code)
Z-Stack
0.26µm
645 x 398 x 420mm
~16 Kg.
Motic
MoticEasyScan Pro 1
1
Brightfield
Yes
Jpg2000,SVS, DICOM
1D: Interleaved 2 of 5, Code 39, Code 128 2D: Data Matrix, QR Code
Z-Stack
0.26µm
645 x 398 x 420mm
~16 Kg.
Motic
MoticEasyScan Infinity 60
60
Brightfield
No
Jpg2000,SVS, DICOM
Barcode scanning
Z-Stack
0.26µm
700 x 398 x 420mm
~33 Kg
Motic
MoticEasyScan One
1
Brightfield
Yes
Jpg2000,SVS
Image-based 1D and 2D (Datamatrix, QR code)
Z-Stack
0.26µm
205 x 398 x 420mm
12.6 kg
Motic
MoticEasyScan Infinity 100
102
Brightfield
No
Jpg2000,SVS, DICOM
Barcode scanning
Z-Stack
0.26µm
700 x 398 x 420mm
~33.4 Kg.
Olympus
VS200 Single Tray
6
Fluorescence, Brightfield
Yes
vsi,tif ,DICOM JPEG
1D Code :39,code128,interleaved 2of 5 codabar ,EAN 8 & UPC-E . 2D Code: DataMatrix (ECC200) QR Code (QR cod model 2)
Z-Stack
0.137 μm
Olympus
VS200 Multiple Tray Loader
210
Fluorescence, Brightfield
No
vsi,tif ,DICOM JPEG
Z-Stack
0.137 μm
Optrascan
OS-FS
15
Brightfield
Yes
1D 2D Datamatrix,Etc
Z-Stack
11x16x15 inches
55lbs
Optrascan
OS-Ultra High-Speed Scanner
480
Brightfield
No
1D 2D Datamatrix,Etc
Z-Stack
<1min
22x27x24 inches
154 Lbs
Optrascan
OS-FL
15
Fluorescence
No
1D 2D Datamatrix,Etc
Z-Stack
14x17x16 Inches
65 Lbs
Optrascan
OS-FLi
15
Fluorescence, Brightfield
No
1D 2D Datamatrix,Etc
Z-Stack
14x24x18 inches
75 Lbs
Optrascan
OS-Lite
15
Brightfield
No
1D 2D Datamatrix,Etc
Z-Stack
1-3 min
11x16x15 inches
55Lbs
Optrascan
OS- SiA
15
Brightfield
No
1D 2D Datamatrix,Etc
Z-Stack
11x16x15 inches
55Lbs
Philips
 SG20
20
Brightfield
Yes
iSyntax
Image based barcode reading
680x800x675mm
150kg
t has market clearance in EEA (European Economic Area), United Kingdom, Ireland and Singapore. Specific conditions apply to the USA market.
Philips
SG60
60
Brightfield
No
iSyntax
Barcode and QR
≤ 62 seconds
680x950x675mm
142 kg
t has market clearance in EEA (European Economic Area), United Kingdom, Ireland and Singapore. Specific conditions apply to the USA market.
Philips
SG300  
300
Brightfield
No
iSyntax
Barcode and QR
≤ 62 seconds
680x950x675mm
150kg
t has market clearance in EEA (European Economic Area), United Kingdom, Ireland and Singapore. Specific conditions apply to the USA market.
Precipoint
O8
2
Brightfield
VMIC, VMS, VMU, GTIF, NDPI, SCN, MRXS, TIF, TIFF, JPG, PNG, GIF, BMP
Barcode and QR
Z-Stack
0.28 μm
45cm x 40cm x 30cm
25kg
Precipoint
M8
2
Brightfield
Yes
VMIC, VMS, VMU, GTIF, NDPI, SCN, MRXS, TIF, TIFF, JPG, PNG, GIF, BMP
Barcode and QR
Z-Stack
0.28 μm
45cm x 40cm x 30cm
25kg
TissueGnostics
TISSUEFAXS FLUO
8
Brightfield
OME-TIFF, TIFF, JPEG, BMP, PNG
Barcode and QR
TissueGnostics
TISSUEFAXS PLUS
8
Brightfield
OME-TIFF, TIFF, JPEG, BMP, PNG
Barcode and QR
TissueGnostics
TISSUEFAXS I HISTO
8
Brightfield
OME-TIFF, TIFF, JPEG, BMP, PNG
Barcode and QR
TissueGnostics
TISSUEFAXS SL
120
Fluorescence, Brightfield
OME-TIFF, TIFF, JPEG, BMP, PNG
1D and 2D Symbology
TissueGnostics
TISSUEFAXS SPECTRA
8
Brightfield
OME-TIFF, TIFF, JPEG, BMP, PNG
Barcode and QR
TissueGnostics
TissueFAXS Histo
8
Fluorescence, Brightfield
OME-TIFF, TIFF, JPEG, BMP, PNG
Barcode and QR
Ventana
VENTANA DP 200 (IVD) VENTANA DP 200 (RUO)
6
Brightfield
Yes
BIF, TIF, and DICOM
1D and 2D Symbology
<85 seconds
19.6 W in x 26.7 Din x 18.2 H in
48 kg 105 LBS
Ventana
VENTANA DP 600
240
Brightfield
Yes
BIF, TIF and DICOM / (ICC)
1D and 2D Symbology
<85 seconds
74Wcm x 74Dcm x 67Hcm
75kg 165.3 LBS

This data is an attempt to compile the various tools available for digital pathology solutions.  Submit your feedback for additions, corrections, questions or comments. 

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